Connecting Gut Health with RA

Connecting Gut Health with RA

Research in recent years has been connecting gut health with the immune system. For example, how people’s gut health can be compromised by taking too many antibiotics that kill the natural flora (bacteria) that we need in our digestive track for breaking down food. If the natural bugs in our gut are not present, they can’t do the job of supporting our immunity against unfriendly bacteria.

Recently, two new studies by the same researcher indicate a connection between gut bacteria and rheumatoid arthritis. The first study found patients with rheumatoid arthritis had a great deal more of a certain kind of bacteria compared to a healthy control group. The second study treated mice with a specific bacterium strain and compared them to a group that received no treatment, finding that inflammatory symptoms reduced in frequency and severity with the bacteria treatment.


In an interview about the studies, the researcher is careful to explain that it is not known if this difference in gut bacteria is a cause of RA or a symptom that follows the illness. But she suggests further study could help with grouping patients by severity, understanding what drug treatments may be more effective, and looking at how diet may affect the gut’s health.

This research is fascinating to me and connects a suspicion that my gut is affected by my RA or vice versa. I sometimes think that I have a more sensitive stomach and wonder if it is connected to my RA or exacerbates it.

I have been taking probiotics for many years and while it is not scientifically proven, I think it has helped with my digestion and also boosted my natural immunity. Once I started taking them, I got sick less frequently.

In the past I have taken many courses of antibiotics, some of it for preventative purposes. But I find that doctors are becoming more wary and sensitive about overprescribing antibiotics because of the potential harmful effects on the gut and also the looming problem of antibiotic resistance.

When I was taking antibiotics intravenously for a long period of time due to a knee replacement infection, the doctor who treated me prescribed daily probiotics. He was concerned about upset stomach, but I was also concerned about the potential long-term effects of killing off my natural gut flora.

There’s a great deal to still learn about gut health and how it impacts the health of the rest of our bodies. More conditions are being connected to poor gut health or deficiencies in the natural flora we are born with. I am not surprised there may be a connection with RA and I am eager to learn more about how good or bad bacteria in my digestive track may play a role. What if this line of research could lead to a discovery of a new array of treatment options or even preventive measures with early testing?

The autoimmune system is highly complex and inflammatory disorders seem to sprout everywhere possible in the human body. Building our knowledge of how the gut contributes to the immune system seems like an important line of inquiry for better understanding and treatment of diseases like RA (and all its autoimmune cousins).

My gut says this is a good idea and is hungry to learn more!

This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The RheumatoidArthritis.net team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

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