Is anyone taking methotrexate? Did it help?

I was diagnosed in January of 2018. I was on plaquenil, and occasionally Percocet for pain. I was still having flare ups. I have been given methotrexate. I’m nervous about taking it. The side effects are frightening.


Community Answers
  • sissixu
    5 months ago

    I take 6 methotrexate pills every week and 1 folic acid every day. And i also take 1 hydroxychloroquin every day. I am 99% pain free now compare to a few month ago before I take methotrexate. Hope you feel better after taking it.

  • marchon.
    5 months ago

    I have taken Methotrexate for awhile, and theres a few things that I have problems with, like being nauseous and after taking the meds getting a headache and sometimes waking up with one. And I think I have lost some hair using this medicine.

  • HopesnHim
    5 months ago

    I was on Methx injections for 16 months and I felt horrible the whole time and my RA actually got worse. But that is me….it depends on the person, some medicines work well for one and not for another. I hope you find the one that works for you!

  • Richard Faust moderator
    6 months ago

    Hi Kim. Sorry to hear about your recent diagnosis, but it is great that you have sought out a place you can get information and support. It is completely understandable that you have concerns about taking methotrexate, but understand that many do take it successfully. This article from our editorial team gives an overview of methotrexate: https://rheumatoidarthritis.net/treatment/methotrexate/. Also, in this article one of our contributors looks at some of the concerns with methotrexate and his experience with it: https://rheumatoidarthritis.net/living/methotrexate-the-ra-drug-many-love-to-hate/. The decisions on treatment are truly personal and, for your protection, we cannot give medical advice over the internet. Hopefully other community members will chime in with their experiences. Wishing you the best and keep us posted on how you are doing. Richard (RheumatoidArthritis.net Team)

  • Kim author
    6 months ago

    Than you

  • MareV
    6 months ago

    I take methotrexate once a week and plaquenil once a day. It has helped me. Of course I still have some joint pain, but nothing like it was when first diagnosed.

  • Kim author
    6 months ago

    Thank you. I’m having some pain now.

  • Lawrence 'rick' Phillips
    6 months ago

    I look forward to taking MTX each week. I also dread it. The reason is that tit works in conjunction with the biologic I use, however I lose at least 1/2 day each time I take it.

  • Kim author
    6 months ago

    If you don’t mind me ask8ng, how do you lose 1/2 day?

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