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A hangover I don’t deserve.

Friday used to be the holy grail of work days for me; you see I am a 9-5’er, from 9am Monday morning you are looking forward to Friday.
Recently that has been flipped on its head, I have begun to dread Friday rolling around.
“How can that be?” I hear you ask.
Well you see on Friday mornings I wake up feeling seedy, with a blinding headache and dog tired.
I know what you are thinking; well you must have had a pretty good night Thursday to wake up that way every Friday…

Want to know about my exciting Thursday nights?
I come home from work and have a good dinner, relax and watch some t.v and wait for my alarm to sound at 8pm; at 8pm I take my weekly dose of methotrexate. I drink some water and I get an early night. Pretty wild huh?

What is methotrexate? Well I will leave this one to the experts says;
“Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung. It is also used to treat severe psoriasis and rheumatoid arthritis.”
Before you get too worried I take a much lower dose than a cancer patient and at the moment I am taking it in a tablet form – no hospitals or needles in sight!

On Fridays I have a heightened sense of smell, I am pretty sure that I could out sniff a blood hound…
Imagine having to carry out your daily activities when every smell makes you feel increasingly nauseated; Perfume feels like a punch in the face, it’s like I can taste it and as much as I love flowers I don’t really fancy tasting them.
Coffee, car fumes on the street, the ink and hot paper from the printer, food smells sometimes incredibly random ones like raw garlic in the main street?! All hit me with waves of nausea. I can only imagine that this is what it feels like to have morning sickness all day… its safe to say I’m not a fan!

So far this treatment is very new, so I am yet to feel any relief to my arthritic symptoms, but I am telling myself that the positive will eventually far outweigh the negative.

A hangover is much more pleasant when it is deserved; you have the fun memories of drinking and dancing with your friends… I don’t even drink anymore now that I am on this medication which is just part of the irony of being hung over every week.

This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.


  • Meg Koelzer
    4 years ago

    I do methotrexate injections weekly – and boy do I dread it. I always feel sick after, whether it’s from the thought of injecting with a needle or a side effect of the medication itself. It does help though! After multiple years I’ve concluded that one night of nausea highly outweighs a week of stiffness and pain. Keep it up!

  • Mariah Z. Leach moderator
    4 years ago

    Hi Tegan ~ A methotrexate hangover can be the worst! I usually take mine on Saturday night. Sucks to ruin part of my weekend but I have to do it when my husband will be home to help with our two little boys if I end up feeling really terrible! Hopefully you will start seeing some benefit from your methotrexate soon. If you are really having a hard time about the side effects you may want to talk to your doctor about taking a folic acid supplement (which can sometimes help with the “hangover”) Also, some people claim to get fewer side effects from the injection than the pills, so that may also be something worth considering! Hang in there!

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