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RA with Cortisol and Prolactin deficiency’s

Hi everyone I am new to the group. Just wanted to introduce myself and ask if anyone has experienced any of the same symptoms that I am currently experiencing.
My name is Wendy, I am 34 with 3 children and a wonderful husband. For over a year I have had complained to my PCP about extreme fatigue. She of course would say well you have a 12 year old and 2 year old twins, you work part time and are a College Student. Get more rest was her advice. Later in 2016 other symptoms occurred. I started having elevated prolactin levels and extremely low Cortisol level which literally left me nearly comatose. All of this year (2017) I have dealt with issues of these extremely high Prolactin and very low Cortisol. I have seen 4 endocrinologist, 4 OBGYN (prolactin causes galactorea), my PCP monthly and finally a Reproductive Endocrinologist. I knew I had arthritis but continued to focus on all the endocrine related illnesses. After weeks of constant joint pain and swelling, I could barely walk I finally went yet again to my PCP and was then referred to Rheumatologist. I don’t have specific numbers, but was told that all inflammatory markers were extremely high and that my levels resembled that of a 65 year old woman rather than a newly diagnosed 34 year old. I am now 2 weeks in with Methotrexate, Prednisone and folic acid.

My question, could RA have caused all these other more endocrine related symptoms as well?? More specific, has anyone else experienced Prolactin and Cortisol issues at the same time as a RA flare up?

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  • Marianne Marden
    2 years ago

    Hi!! I haven’t been on here for a while. I read your question at just the right time to help you out. I had gone through the exact same situation, but I am 60 now. I have very interesting information to share with you. Please email me at I hope it is okay admin for me to share my email.

    Looking forward to hearing from you Wendyhill…..


  • Erin Rush moderator
    2 years ago

    Hi Wendyhill! I am glad you found this community! Welcome! I am glad you shared a part of your story with us.

    While we cannot provide medical advice or diagnosis, for your safety, I will say that hormones and how they relate to RA are a topic of ongoing study and interest within the RA medical community. Here is some information on RA and possible connections to hormones — It is definitely an area that needs more research!

    I do hope that your treatment protocol starts yielding some noticeable, positive results very soon!

    Thank you again for sharing and please let us know if there is anything we can do for you. We are happy to help in any way we can.

    Best, Erin, Team Member.

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