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Plaquenil and Prednisone

  • By Ang

    I have been on plaquenil for about 3 months and prednisone for about 5 months. Daily I still get pain and stiffness in my hands and feet. I also have lost weight without trying and losing my hair is this a side effect of my medicines? I also take gabepentin and vitamin d.

  • By Andrew Lumpe, PhD Moderator

    Hi Ang, you should speak to your doctor about any symptoms and medication side effects.

  • By Connie Rifenburg

    Ang, I had hair loss pretty severe when I first started on Prednisone, Plaquenil, and Methotrexate. I guess it may depend on the dosage, and hopefully your hair loss will stop as mine did after a few months. My scalp was very sensitive at that time too and it hurt just to shampoo. In my case, it stopped and altho I have what I consider ‘thinning’ hair, it may or may not be due to my meds now, but it definitely was related in the beginning.

    I didn’t stay on Plaquenil for long tho since it had an almost immediate reaction to my eyes. I know this is a side effect for some people and you should be regularly seeing an opthamologist while you are on Plaquenil (I’m not a dr, but I do know that it is usually brought to your attention when they put you on this particular medicine).

    I certainly didn’t lose any weight – and really gained fat in places I never had it before when I went on Prednisone. (I used to have an angular face – it can’t get much rounder now tho);-)

    I take 5000 units of D3 everyday and did find that I had quite a low Vit D when I don’t take it

    I would make sure to tell your RA dr. about all your symptoms in your next visit.

    I hope the meds will kick in soon to help with your pain. There is always that period of time of waiting before we notice improvements. Hang in there.


  • By GailPatricia

    Unfortunately we are all different and meds act different . You have to keep track of you reactions and discuss with your doc on next visit. Prednisone is a bone killer as I’m paying the price 25 years later, but I was pretty pain free all those years! No hair loss and plaquenil has not affected my eyes other than dry eyes. Keep a diary of your meds.