I was dx 14 months ago by a rheumatologist with “seronegative” RA. No positive markers, no elevated inflammatory markers. I had all of the RA symptoms I’ve seen here except for redness or abnormal labs. I was started on Plaquenil and it helped but after 6 months I was changed to Methotrexate due to itching. I was on that for 6 months, it about did me in. I had just started Leflunomide when I went to a Cleveland Clinic rheumo who said I don’t have RA because of the above lack of symptoms. Now I’m so confused I don’t know what’s going on. Can I get some prospective from you on this forum?