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Syringe vs. Auto-Injector

Many biologic medications used to treat RA can be administered with an auto-injector or a syringe. In the second of three videos on RA biologics, I share my opinion on auto-injectors versus syringes and aspects of both that people may prefer or dislike. In my experience, syringes are a potential option for those who may not like the blast of the autoinjector and would like to try something different.


This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.


  • calgirl
    4 months ago

    Hi, I have used the auto-injector since I got diagnosed with RA over a year and a half ago. I don’t always bruise ( I use my upper thigh) but when I do, it is a severe bruise, lasting almost two weeks. Have you heard anything about the difference in bruising between the two? I would definitely look into a syringe if it would reduce the possibility.

  • Richard Faust moderator
    4 months ago

    Hi Michael. Thanks for putting this information out in an easily understandable format. One note that I would add concerning the autoinjectors is that they can be beneficial for those who can’t or have difficulty doing the injection themselves. I do my wife’s autoinjection and could certainly learn to use the syringe. However, if I was unavailable, she could pretty much have anyone do the autoinjection, but that is really not the case with the syringe (a little more training required). I know this is a small percentage, but can be a consideration. Best, Richard ( Team)

  • Lawrence 'rick' Phillips moderator
    4 months ago

    Micheal I am a total syringe person. Something about the control Of placing the needle against the skin is best for me. I hate the anticipation of the auto injector,, I long for the control. Always control.

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