I started on Orencia 8 months ago, and after 4 or 5 months I started to feel better but I never got back to how I felt prior to my last flare. Pain level at its lowest is a 4, and is generally around 5 or 6. I accepted this is my new normal, as with the exception of the few days before my infusion, (and around my menstrual cycle when I always flare) I have been able to get housework done, and interact with my kids which is really all I need. However this month my symptoms improved 0% since my infusion 2 weeks ago. It's like I never received an infusion at all.