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Anyone on a JAK medicine?

Could you tell me what side effects you have had? I was on Humira and had major depressive side effects. I am currently on nothing but am being told to try Olmiuant 2mg. I am basically afraid of having any type of reaction which limits my quality of life. I am 79 and currently volunteering, socializing with family and friends, fixing up my house, tending to my dog, etc. I do not care if RA is impacting my organs. I just want to be able to have a good end of life, however long that may be. The rheumatologist doesn't seem to understand that. He thinks I have to take medicine to stop the bone erosion. I am not sure what to do.

  1. Hi . I have no experience with JAK medications, but I thought this article and the associate comments might interest you: https://rheumatoidarthritis.net/living/jak-inhibitor-reviews. I hope you get lots of responses from the community and that your are able to make a decision with confidence. Thinking of you. - Lori (Team Member)

    1. Hi . Like , I don't have any personal experience to offer, but I want to share with you this article from our editorial team which gives an overview of how JAK inhibitors are different from biologics: https://rheumatoidarthritis.net/clinical/jak-inhibitor-biologic-comparison. In addition, I can tell you that my wife, Kelly Mack (a contributor here), was on Xeljanz for a period, but it was not terribly effective for her and she had gastrointestinal side effects and headaches. That said, every individual is different and many in the community have had great success with JAKs. In fact, one JAK can perform very different from another for an individual person. I now on one level that is not terribly helpful, but it is simply true that you will not know for sure what the impact will be until you try it. Wishing you the best and hope that, if you choose to move forward with the Olumiant that it is effective for you with minimal side effects. Richard (RheumatoidArthritis.net Team)

      1. I am allergic to Jak

        1. HI . Was there a specific drug you were on? I ask because the various JAKs have different actions within the body and chemical compositions. Have you find a medication that has helped? Best, Richard (RheumatoidArthritis.net Team)

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