I am a 25 year female who was diagonized with RA in 2013 after having mild pain in shoulder followed by swelling in the ankle. I went to see a Rheumatologists within a month. The doctor took complete blood tests to see my RF- 54 and Anti-CCP- 40 and others blood tests were normal. He put me in 15mg of MTX and Hydroxycholorquine 200 and Folic acid 5mg tablets. After the first incident on 2013 that I had no flare, no morning stiffness. I continued and still continuing those medications. Recently, in April 2016, I took up blood test to see that my RF factor went to 34 whereas my Anti CCP rocketed to 453 UI/ml CRP is 0.463 (normal) Still I don't find any flare or morning stiffness. Since the CRP was less the internal medicine doctor said there are no inflammations however it is better to consult my Rheumatologist.
I am clueless of sharp increase of my anti CCP value and decrement of RF factor. Is this something serious to be taken care regarding the change of medications? Is my disease evolving?