Help determine the diagnosis
Hi. My English may not be perfect since I am not a native speaker, but I hope for your help and advice....
In 2017, when I was 14 years old I was diagnosed with rheumatoid arthritis(one morning I woke up with a swollen knee that hurt and limited my movement). Before that I was often bothered by my throat, strep was found. HLAB-27 negative, rheumatoid factor negative, ANA negative. Only C-reactive protein was elevated. I was prescribed methotrexate, but I did not take it for more than 2 years, as my body did not accept it anymore. After treatment of the intestines or somehow by itself everything became fine, no knees were not swollen, nothing hurt.
And now I have been without medication, without therapy for at least a year since 2020 and nothing bothered me in principle. But somewhere during the last half a year there appeared sometimes "walking" pains, but not only in the joints, also in the muscles and as if the bones. The pains are mild and do not require painkillers. Everything is still normal according to tests, ultrasound and X-rays too. I am interested in the question - could I have been misdiagnosed? Can "seronegative rnvmatoid arthritis" have such a good clinical picture, or to look for the cause in something else? Does RA hurt bones and muscles all over the body, not just joints? Especially nothing swollen, no stiffness in the mornings.
Please help 🙏 Health to all!
Thanks for the message. Your English is great by the way! Determining a diagnosis is difficult as we are not doctors so your unique medical history is going to be a big part of determining a diagnosis. So I would first refer to your individual doctor. But you asked some questions around seronegative RA and I want to share with you our seronegative RA Hub that may point you to some potential answers: https://rheumatoidarthritis.net/seronegative-blood-test Others may chime in but I wanted to share this with you! Warmly, - Reggie, RheumatoidArthritis.net team member 
RA is a systemic disease which means anything is fair game when it comes to aches and pains. Many people with RA experience joint pain without swelling and other types of pain so while you don't have any swollenness or stiffness, there can be some other underlying issues. This condition affects everyone differently, and symptoms can change over time. All in all, it will be best to continue to have discussions with your doctor and advocate for more testing to weed out other possible conditions as much as possible. Getting a clear diagnosis can be challenging but don't give up. I hope you can get some answers soon to lead you in the right direction of recovery nd relief. All the best, Latoya (Team Member) bella20 RA is a systemic disease which means anything is fair game when it comes to aches and pains. Many people with RA experience joint pain without swelling and other types of pain so while you don't have any swollenness or stiffness, there can be some other underlying issues. This condition affects everyone differently, and symptoms can change over time. All in all, it will be best to continue to have discussions with your doctor and advocate for more testing to weed out other possible conditions as much as possible. Getting a clear diagnosis can be challenging but don't give up. I hope you can get some answers soon to lead you in the right direction of recovery and relief. All the best, Latoya (Team Member)
