I was diagnosed in April 2013 with RA and have been taking methotraxte since then. I experienced some relief but my doctor is hoping for more and has increased my dosage to 20mg/week. I will be seeing him in about a month to discuss. In the meantime I think I may be experiencing new symptoms. I sometimes feel soreness and stiffness in my ankles and wrists that I never noticed before. Could this be possible? Somedays I am in so much pain that I think it may be difficult for me to distinguish between old and new!