Hi Effie, i do use curcumin in the phytosome formulation for better absorption. I've used it for years, and it works almost as well as prednisone if I take two caps 3x a day. I have not had any gastro side effects, which may be due to the phytosome preparation. I recently started Boswellia, and it works very well. I read a study on NIH about Berberine, and have added it because it may help RA. I always stop all these 2 weeks before I get blood tests, so that the true inflammation values are reflected. The doctor isn't into natural supplements, so I don't mention it. Some of these supplements are said to not only improve symptoms, but may slow the disease process, too. I'm hoping that's the case, since the pharmaceuticals haven't worked, and i can definitely tell a difference when I stop taking the natural supplements.