From my experience talking with other patients and friends over the thirty plus years of my own RA, I learned that many times during pregnancy they take the person off most of their RA meds. That is definitely something that could have impacted her pain levels and disease activity level. Unfortunately RA is a game of trial and error that can take years and years to find the right medicine combination. It took me and my doctors two decades to find a biologic and med combination that works to control my illness so I can only say that I know it's difficult but don't give up. You can find the right combination, it just takes a while sometimes. In the meantime if there's anything we can do to help, let us know, and let her know she is not alone! Keep on keepin' on, DPM