I have been on Remicade before. It didn't work in the end for me, and after about 12 months or so we decided it wasn't working well enough to continue. I never had any bad side effects or anything, but it just wasn't working on my illness really as well as it should. It took me 20 years, in fact, to find the right medicine for my specific illness and for me, it's Kineret, an interleuken-1 inhibitor, and that seems to keep my illness at bay. Wishing you luck in your search and remember you can always come here to be with others who really get it! You are not alone. Keep on keepin' on, DPM