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Severe RA and treatments

My husband was dx with severe RA over a year ago. So far no meds or combination of meds have done anything in the way of slowing things down. methotrexate, Plaquenil, daily low dose prednisolone and occasional packs and shots, Rinvoq and now Enbrel.

Why is this happening? Why can’t something work already? Is it because the RA is severe? Is it because he also has mild osteoarthritis? Is it for some people- there is not going to be enough relief to feel better? I realize it may take time to find the right meds- but the wait is awful while it progresses. And I wonder if there is a right mix for him. It is so sad and frustrating my and exhausting to see him like this. And it is harder in him to deal with. Just curious about any one’s thoughts with treatments for sever RA.

  1. , first off, I am sorry you and your husband are dealing with this. Watching a partner suffer is incredibly gut wrenching, I know.


    I wish I had some magic answer for you, but, unfortunately, it can take a fair amount of time and a lot of trial and error to find the treatment that works best for each individual. I know. That's a pretty disheartening answer, especially when you're already feeling pretty exasperated by the treatment process.


    Have any of those treatments brought your husband any measure of relief? I only ask because many individuals do experience (temporary) relief with treatments like prednisolone, but they sometimes have to stop the medication due to side effects or concerns over long term side effects from steroid usage.


    Has your husband's rheumatologist been communicating well with you and your husband?


    While OA does add some complexity to your husband's situation, it shouldn't cause that much of an issue in finding effective treatments.


    It really probably boils down to what I wrote above -- it sometimes take time and trial and error. That said, having the patience and strength to endure that when you are hurting and in pain is easier said than done.


    Please know you and your husband are not alone here! I know it can feel like no one understands what you are going through as a couple, but we have a large, diverse community that knows what it's like to be in your position.


    Please don't hesitate to reach out if you have more questions or even if you just need a safe place to vent.


    I hope the next treatment your husband tries does the trick and he starts feeling better asap.


    Gentle Hugs, Erin, RheumatoidArthritis.net Team Member.

    1. mewilbanks, Your concern for your husband really touches my heart. Too often it takes several attempts to find a good treatment. It is frustrating and can be saddening. Personally, one of the things that most frustrates me is how many weeks or months we must give each new treatment trial before we know if it can work. Perseverance is important. And the support of our loved ones as we persevere. I wish I could tell you when and what solution will come your way to give your husband relief. Your loving help and support are essential. Please share here anytime and look for those people sharing their success stories. I hope you also have a close friend or family member available to support you. With Hope and Best Wishes, Jo

      1. He went to a new dr yesterday (non RA). After some extensive bloodwork it was found that two possibly three meds (non RA meds) are contributing to his fatigue and muscle aches and pains. Working to eliminate two and change one. Also bloodwork shows anemia which we knew about but no one addressed. And then there was one other personal medical issue in his bloodwork that had been contributing to the fatigue and muscle aches and pains. So I feel hopeful that much of this is caused by some of his other non RA meds. And once all of this is addressed properly. We may find out that it isn’t his RA or RA meds causing the bulk of his symptoms pains or complaints. Yesterday I learned not only the importance of communication but that doctors need to share information better. And that we need to ask more questions. And insist on better communication. So we have a new starting point while we wait to see if Enbrel works for him. Thanks for your thoughts and support.

        1. , I am so glad to read this update! I know it's not that everything is okay, but it sounds like there's a light at the end of the tunnel and you guys have some answers now. And you are so right -- communication is SO important! We frequently suggest that people write down any questions they have before an appointment. Sometimes, taking another person is super helpful too, so you have two people to ask questions, process information and one person can maybe even be writing things down. Personally, I always think I'll remember things and I don't need to write them down and inevitably, I DON'T remember things!


          Thanks for taking the time to update us and feel free to keep us posted on your husband's progress, if you feel comfortable doing so.


          Best, Erin, RheumatoidArthritis.net Team Member.

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