Hello , I did the Simponi Aria infusions for several months, with mixed results. I would say that I felt maximum results at around 4 infusions. Sometimes it can be hard for me to get accurate result because I have both RA and PsA, but it really worked for my back, shoulder, and elbow pains (which is where the majority of my RA is.) Best of luck with it a be sure to come back and let us know how you are doing! 😀 -Leanne, Community Moderator