I just wanted to chime in and say that I have been on a low dose of prednisone for years, and probably will be for life. Between 4-10mg a day, depending on need. That, combined with a biologic, has seemed to do the best that I can expect from modern medicine right now, but it is enough I feel like. At least for now! It takes a long time to find the right combination of meds for your individual illness - it took me over 20 years! It's frustrating but it can be done. If there's anything else we can do to help, let us know! Above all, just know you are not alone - so many of us have been where you are! Keep on keepin' on, DPM