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I have rheumatoid arthritis I take methotrexate it was help a little my doctor started me on enbrel for my hands I taken 6 shots and it’s not helping yet just wanted to know how long it took to work for others.

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  • Gayle
    5 years ago

    I just started my fourth month with Enbrel and I think 1 1/2 months with Plaquenil. I can’t say I’m in remission and have flareups all the time. I understand how you feel. It’s also a roller coaster, once in a while I fell good like I did today. I bet tomorrow I won’t! I sleep until 1:00, but of course I’m up on the Internet at I know my schedule is messed up but I truly am tired and don’t want to get out of bed. I’m seeing a new RA doctor 12/30. I’m hoping that maybe the medications are starting to work. I never forget an injection or my pills. I hope it starts to work for you.. And me too..

  • Ali
    5 years ago

    I was on methotrexate and it wasn’t enough so we added Humira. It took months for me to notice a difference. I hope you find the right combo of meds ASAP.

  • Mariah Z. Leach moderator
    5 years ago

    Hi Melanie ~ One of the most frustrating aspects of RA is that medications that help one person may not necessarily help another. For example, Enbrel helps me a lot – but Remicade never worked for me. So it can be a frustrating process of trial and error to determine whether a treatment is going to be a good fit for you. I can’t remember how quickly the Enbrel started working for me, but if you are talking about more than 6 weeks with no improvement it is probably time to check back in with your rheumatologist. He/she can give you a better idea of whether you need to hang in there a little bit longer or if it is time to move on and try another treatment. Best of luck to you!

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