Hello, , I'm so glad you reached out. You mention being on Cimza for some time, so I'm not sure if this is relevant or not, but sometimes RA treatments can take as little as 1-2 weeks to notice some relief but up to as many as 12 weeks. (I know, 12 weeks feels like forever when living with RA pain!) That being said, it certainly doesn't hurt to reach out to your doctor and ask about the length of time you should stick with the Cimza before deciding it is not the right medication for you, and what they recommend moving forward. Hopefully some of our community members with person experience with Cimza can also share with you here. I do hope that you can get some helpful information and some relief soon! -- Warmly, Christine (Team Member)