I have major depression that no longer responds to medication. I started Cimzia in April. I've noticed since then I am constantly irritable and my abdomen is bloated and gained weight and other side effects. My insurance does not cover the full cost and I have to pay $2000 (my deductable); but my doctor strongly disagrees with my choice of finding a different med. My question is if others have had the same side effects and experiences similar to mine - especially the irritability. Thanks.