Has anyone taken Fluconazole while on Methothrexate?

Hi jesiandrea! Apologies on the delayed response! I do hope some members see your comment and can chime in. I will say that there don't appear to be any contraindications between methotrexate and fluconazole. However, it's always good to check with you physician or pharmacist before adding any new medication to your routine. Pharmacists are usually up-to-date on the latest information about potential issues of any medications. Good luck and thank you for reaching out! Best, Erin, RheumatoidArthritis.net Team Member.