Does anyone have RD that is hard to treat? My rheumatologist has thrown just about everything at my RD with either no effect on my RD or if it did help it didn't last long. I'm on Rituxan now and I am hoping the second round does better than the first, because this is the last drug I have not failed. What happens when all the RD drugs fail? My Dr. tells me to hang in there, but honestly the pain that never goes away is like torture... I just need some relief!