Leflunomide

Hi . I am sorry leflunomide doesn't seem to be working well for you. Some medications can take six to eight weeks (or longer) to reach efficacy, but since you have been on it for six weeks, it may be worth a call to your physician to discuss your options. And I do hope other community members see your post can chime in her and share some helpful input.


Best, Erin, RheumatoidArthritis.net Team Member.

I took leflunomide for a few months about a year ago. It really helped my RA symptoms and I was very sorry when I had to stop taking it. The side effects, especially diarrhea, made it impossible to continue. Even after stopping it I had a reprieve from my worst symptoms. The fatigue which plagued me since first becoming symptomatic nearly vanished. And now, a year later and at least nine or ten months since stopping the drug, my fatigue isn't as bad as it was before I took it. Don't understand this at all. There may be no connection. It is great though. Sorry it isn't working for you!

I had those too.