I’ve been on Methotrexate now for 1 year , I inject on a Sunday, I feel so tired and low for three days after ,also a wave of sickness comes over me now and then . I still have pain in the mornings , I look forward to Thursday as things start to feel better . Then coming up to Sunday I have a feeling of dread as I know it’s nearly time to inject again . I am seriously thinking of stopping the medication altogether. Has anyone any thoughts on this ? Thanks 😊 Wendy.x