Hi - thanks for your inquiry. In addition to Rick's great comment - I want to follow-up and share that LSD and MDMA are currently illegal is *most states. Oregon and the District of Columbia residents voted to decriminalize the use of magic mushrooms and other psychedelic substances with restrictions - (not making them legal, but making them among the lowest enforcement priorities for law enforcement). All of that said, before mixing biologics with ANY medication - please consult your doctor first. He or she will have insight in YOUR personal medical history and how it might impact you. Thanks for your question! - Reggie (RheumatoidArthritis.net Team Member)