Hello Sanjay! I am not a doctor but I have had RA since I was a baby. It was a juvenile form of RA and was very devastating and crippling. Diet changes help with the pain but they do not cure the disease. Anti-inflammatory medicines help to control the swelling, which is where permanent joint damage occurs. If you keep the inflammation down, you can prevent serious joint damage. I have learned this from my experience. Her doctor can prescribe something perhaps, or simple ibuprofen over the counter can help to control inflammation. As far as diet changes, it helps me to eat all plant-based foods. This helps with inflammation but it does not eradicate the disease, at least it doesn't for me. The rheumatoid factor can fluctuate. I have tested negative for the rheumatoid factor, even while having a serious flare-up. During a better period recently, I tested positive for this factor. This test is not always reliable. The ANA test is more consistent, for which I have alwayes tested positive since my childhood. (It is typical for people with RA to be ANA positive.) I wish you the best and will pray for your sister. My faith in Christ has helped me and strengthened me throughout my whole life with this painful disease. I work as a cyber school teacher and can teach from home, without being in pain from standing and walking all day. I just received June's Featured Employee of the Month. It is important to persevere through the pain and keep active, as this helps both physically and mentally. Hang in there and give my warm regards to your sister!