Thanks for the info. It helps to understand the big picture. I, too, am on Humira; add to that MTX and a bunch of other non-RA drugs.
I think Pred is a wonder drug. Before I went on Humira [about 15 years ago], and the MTX by itself wasn't working well, I was getting corticosteroid shots in many of my major joints. It was a godsend. However, FOR ME, Pred pills make me rebound when I get off them. [I've had to go on the Pred pills for COPD bronchitis flares.]
Pred is not meant as a long term solution. It's to get you over the hump. So hopefully you will start to wean off the Pred. You might find those up's and down's will go away when you do.