Does anyone take Leflunomide daily and Methotrexate once weekly?

Hi lobdell. As Erin mentioned, hopefully some members with actual experience with the leflunomide (Arava) and methotrexate combination will chime in. In addition, thought you might be interested in this paper from Johns Hopkins University finding the combination to be “safe and efficacious:” https://www.hopkinsarthritis.org/arthritis-news/the-combination-of-leflunomide-arava-and-methotrexate-is-safe-efficacious-for-the-treatment-of-rheumatoid-arthritis/. Best, Richard (RheumatoidArthritis.net Team)

Hi lobdell! I do know that at least a few of our members take (or have taken) both Leflunomide and Methotrexate to treat their RA. However, I do not know that their particular treatment plans entailed. Hopefully, some of them will chime in here! I hope this treatment plan is working well for you, if you are on this particular protocol. Best, Erin, RheumatoidArthritis.net Team Member.