Hi there YoungGirlRA, Thank you for reaching out with your question. It's extremely important to discuss your medications with your doctor and/or Pharmacist to be aware of any potential interactions or contraindications. In some cases taking two medications together may effect their effectiveness. In addition to speaking with your doctor, these articles may be helpful to you: https://rheumatoidarthritis.net/women-health/ and https://rheumatoidarthritis.net/treatment/enbrel-reviews-how-does-it-work/. Wishing you the best. Kelly, Rheumatoidarthritis.net Team Member