and Thank you both for responding. Even though I was diagnosed with RA abt 25yr+, the immediate allergic reaction to Prednisone has kept my doctors leery of prescribing steroids (shots are okay) until this last year. This is only my 2nd time having to use this medication. The first time, 10 months ago, I was in the hospital for 5 days and was watched like a hawk for reactions with a 10 days at home after. This is when the effects happened. Currently prescribed the Dexamethasone 6mg once a day, for a 10 day period, just finishing my 3rd day ready for a 4th dose as I write. Not noticing to many side effects this time so far, but my RA Lungs are not as bad as they were before, a little gitty, insomnia has worsened a little. Thank you for letting me know that I am normal. LOL The mood changing, if they arrive again, was "depressive moods" no anger thank goodness. On a good note, it is giving me some relief through out my body. Yeah! Guess with this go around, I will just have to be vigilant and go with the flow. Thanks so much again for your responses, grateful for you all!