I've actually had this drug twice - once for rheumatoid arthritis and once for cancer. Both times I did have a bit of neuropathy but I was never told it would help with that. Even so, the neuropathy did go away but I can't say for sure if it was due to the Ritux... I do know that it does take a while for neuropathy to dissipate if it goes away at all, if that helps. Keep on keepin' on, DPM