I believe Hyrimoz is the biosimilar for Humira? I did get itchy welts near my injection site. In fact, older sites would flare with new injections, more so on my abdomen than thighs. At the time, I was told if it was limited to the injection site, just watch it. I’d take pictures of the rash. It would be good to check with your prescriber or pharmacy and describe your reaction. They should be able to help you know how significant your reaction is. Or, if it may be due to something else? Jo