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Ibuprofen side effects

I need something for pain sometimes. My dr. has prescribed ibuprofen previously. Since my liver enzymes continue to be a problem he doesn't want me taking it. (I take very little, only when I can not stand it or it has gone on for days.) I also take Rinvok. My only alternative( that I can see is to stop both medications. Which is most important to try to manage the pain with the meds or stop and let my joints self destruct?

  1. Hi . You are not alone. Many people reach a point where they can no longer take NSAIDs, often for the same reason. So I hope you get lots of input from the community. Here is an article from one of our advocates about RA and pain relief that might interest you: https://rheumatoidarthritis.net/living/accessible-pain-management and here is another https://rheumatoidarthritis.net/living/pain-relief-trailblazer. I hope these help and that you get some good feedback from others. Wishing you the best. - Lori (Team Member)

    1. Hi . It is true that Rinvoq can increase certain liver enzymes (see: https://www.medicalnewstoday.com/articles/drugs-rinvoq-side-effects#:~:text=Rinvoq%20may%20cause%20increased%20levels,a%20sign%20of%20liver%20damage.) Has your doctor discussed other possible medications, such as biologics (note: while many associate Rinvoq with biologics, it is actually a JAK inhibitor)? This conversation would seem particularly useful if it also seems the Rinvoq is not controlling your RA and you are still in substantial pain. Hoping you can get some answers and relief soon. Best, Richard (RheumatoidArthritis.net Team)

      1. I have tried several biologics in the past. Thank you

        1. My liver panel has been fine. I however felt that I was taking too much Ibuprofen. I have been taking once daily . It can take 4ish days to really feel like it was working. You should not take NSAIDS like Ibuprofen when on this med. I had 2 flare -ups and took Tylenol. (Not sure that really helped)

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