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Does anyone else take both naltrexone and methotrexate?

I am currently taking methotrexate and just within the last week have started taking low dose naltrexone. Does anyone take these two drugs together or does one cancel out the effectiveness of the other?

  1. Hi farmwife. Hopefully some others will chime in with their experiences. For your protection, we cannot give medical advice over the internet. Your doctor should be able to tell you if methotrexate and naltrexone are contraindicated. I have not seen any references to that effect, but that certainly does not mean they are not out there and that it couldn't be an issue. You may also want to ask your pharmacist, as they are often knowledgeable on drug interactions. Wishing you the best. Richard ( Team)

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