Why is my pain increasing if my levels are normal?

My CPR levels are normal, but my swelling and now pain is increasing??

I’m on methotrexate and have been on Humira for 7 weeks. Had anyone else had this experience, and were they given a good explanation of what is happening?


Community Answers
  • Monica Y. Sengupta moderator
    7 months ago

    Hey Michelepike23, I just wanted to piggy-back from Richard. Have you been diagnosed with sero-negative RA (normal bloodwork but clinical symptoms)? This article has more information on this diagnosis: https://rheumatoidarthritis.net/living/seronegative-ra-blood-tests-dont-tell-entire-story/

    Hope these new meds help soon! ~Monica

  • Richard Faust moderator
    8 months ago

    Hi michelepike23. Sorry you are having this difficulty. As with any new symptoms, you should bring this to the attention of your doctor – especially since you are on a new treatment. Also, biologics can take a little while to kick in – you didn’t mention how long ago the blood test was. Hopefully some others have experiences to share. Wishing you the best and keep us posted on how you are doing. Richard (RheumatoidArthritis.net Team)

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