Fatigue and mood changes can happen with biologics so it's not uncommon, especially in the beginning phases. As Richard mentioned, you should definitely speak with your doctor. But in the meantime, I encourage you to track your symptoms, create a simple daily routine, and get some sunlight and movement going if you can. Even small efforts can make a difference while your body adjusts. Hang in there and take it one day at a time. Kindly, Latoya (Team Member)