Sorry, I'm just assuming when you say "they" you mean you or someone close to you in which case I think the first step is always going to be checking with your physician. For me, personally, since I've been with my rheumy for so many years, he trusts me to move up my steroid dose when I need to. I do it only when I am feeling bad enough that I know that a 2-3 day prednisone blast will get it back under control. This comes with years and experience, unfortunately. Hopefully this helps! Keep on keepin' on, DPM