Hi Brenda (). Thanks for sharing. , what Brenda said here about finding the right medication to often be trial and error, but possible has definitely been true for many in the community. My wife, Kelly Mack (a contributor here), was diagnosed at age two, 46 years ago - before modern treatments, with the damage to show for it. About seven years ago she started a new treatment that brought her inflammation levels into the normal range for the first time. I'm tagging our team member , who I know had a similar experience, but who also has experience with pain management. Best, Richard (Team Member)